Sailor Piece
B Tier

Blood Rune

Bleed DoT Damage

Inflicts a bleed effect on enemies, dealing damage over 5 seconds. Blood Rune scales from 65% bleed damage at base to 97% at max level. Longer duration than Inferno Rune but slightly lower total damage.

Updated 2026-03-15

Tier Position

#8 of 11

Location

Rune Dungeon — rare drop

Max Level

Lv50

Cost

Free (drop)

At a Glance

Blood Rune

B Tier

Ranked #8 of 11 in Runes

Bleed DoT Damage

Tier Distribution

S+
2
18%
S
3
27%
A
1
9%
B
3
27%
C
1
9%
D
1
9%

Blood Rune is in B Tier

Bonus & Scaling

Bonus TypeBleed DoT Damage
ScalingBase: 65% total DMG over 5s → Max (Lv50): 97% total DMG over 5s
LocationRune Dungeon — rare drop
Cost (Fragments)Free (drop)

Rune Leveling

Max Level
Lv50
Duplicates Needed
502
Equip Limit
1 Rune

Runes are leveled by feeding duplicate copies. Each level increases the rune's bonus. Only one rune can be equipped at a time, so choose wisely.

Usage Tips

  • Damage runes are the most versatile choice, boosting all damage output universally.
  • Pairs well with high-DPS fruits and swords for maximum burst damage.
  • DoT (Damage over Time) runes provide sustained damage, great for extended boss fights.
  • Less effective in PvP where burst damage is preferred over sustained damage.
  • Only one rune can be equipped at a time. Prioritize leveling your primary rune to Lv50 before investing in others.
BleedDotDamageBoss-Farming

Synergy Recommendations

Best Fruits to Pair

Dragon Fruit
PvP synergy
S+
Fiend Fruit
PvP synergy
S+
Kitsune Fruit
PvP synergy
S+
Light Fruit
PvP synergy
S

Best Races to Pair

SwordBlessed
PvP race
S+
Galevorn
PvP race
S+
Sunborn
PvP race
S+
Servant
PvP race
S+

Recommended Builds

Warlord + Strongest Shinobi
Endgame
SwordBlessed + Gilgamesh
PvP
Galevorn + Anos
Endgame
Leviathan / Servant
Endgame